milk thistle depression milk thistle depression
Little is known about whether its safe to use milk thistle during pregnancy or while breastfeeding. The site is secure. Clin Exp Pharmacol Physiol. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. However, there are currently no human studies, so its effectiveness remains unclear. 5 It was found that there was no significant difference between milk thistle and Prozac for OCD symptoms. Silymarin is believed to have antioxidant properties. People who have diabetes or endometriosis should check with a doctor before using milk thistle. Eur Endocrinol. Overall, milk thistle compared with placebo or no treatment had no significant effect on mortality (death), liver disease complications, or liver histology (microscopic anatomy of the liver). include protected health information. 2008;47(2):605-12. doi:10.1002/hep.22044, Voroneanu, L.; Nistor, I.; Dumea, R. et al. Biomed Pharmacother. Theres conflicting research on the benefits of milk thistle for liver health. This prickly plant has distinctive purple flowers and white veins, which traditional stories say were caused by a drop of the Virgin Marys milk falling onto its leaves. 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Herbal product use by persons enrolled in the hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial. However, there is a lack of . Milk thistle is primarily taken in supplements sold as tablets, capsules, or extract primarily to help with liver function. The NCCIH Clearinghouse provides information onNCCIHand complementary and integrative health approaches, including publications and searches of Federal databases of scientific and medical literature. Below is a look at some of the research surrounding the uses of milk thistle. In test-tube and animal studies, silymarin has been shown to prevent oxidative damage to brain cells, which could help prevent mental decline (16, 17). The research on milk thistle's use in cancer patients is promising, although more research is needed to determine its benefits. doi:10.1515/jbcpp-2019-0206, Kazazis CE, Evangelopoulos AA, Kollas A, Vallianou NG. 2015;22(2):290-6. doi:10.1016/j.phymed.2014.12.010. Ask a doctor, pharmacist, or other healthcare provider if it is safe for you to use this product if you have: an allergy to plants such as ragweed, chrysanthemums, marigolds, or daisies. J Diabetes Res. Anyone have experience with Milk Thistle for OCD/Anxiety? U.S. Department of Health & Human Services, 9000 Rockville Pike Bethesda, Maryland 20892, U.S. Department of Health and Human Services. Tadaah, perhaps a partly explanation for your experience? Herbal product use by persons enrolled in the Hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial. 5th ed. Mayo Clinic does not endorse companies or products. Milk thistle is a popular herbal remedy that has been used for its therapeutic effects for centuries. While more research into milk thistle, silymarin, and its effectiveness in treating OCD is definitely needed, there is a wealth of information supporting the other health benefits of milk thistle for a host of ailments: Liver Health It is believed that milk thistle and silymarin bolsters liver function by prohibiting toxic substances from binding to liver cells (6). Mastron JK, Siveen KS, Sethi G, Bishayee A.Silymarin and hepatocellular carcinoma: a systematic, comprehensive, and critical review. Common side effects of milk thistle reported in studies include: Typically, side effects will subside once you stop using milk thistle. As a result, researchers suggest that milk thistle may be a useful therapy for preventing or delaying bone loss in postmenopausal women (24, 25). 2022 Dec 7;19(24):16426. doi: 10.3390/ijerph192416426. (silymarin) extract supplementation on antioxidant status and hs-CRP in patients with type 2 diabetes mellitus: a randomized, triple-blind, placebo-controlled clinical trial. Zhang Z, Wu H, Qi S, Tang Y, Qin C, Liu R, Zhang J, Cao Y, Gao X. Int J Environ Res Public Health. The https:// ensures that you are connecting to the Healthline Media does not provide medical advice, diagnosis, or treatment. *These statements have not been evaluated by the Food and Drug Administration. A 2010 review by researchers found that black . Combining silybin with phosphatidylcholine and other phospholipids enhances the absorption of milk thistle's active compounds, providing powerful liver health support. Read our. Although some studies have shown positive results on milk thistle for people with chronic hepatitis C virus (HCV) infection, the overall research does not show a benefit. Eighteen clinical trials of 1,088 participants were assessed. The Gale Encyclopedia of Alternative Medicine, second edition, 2004. Milk thistle is a popular herbal remedy best known for its liver-protecting properties. In a mini Review on the Chemistry and Neuroprotective Effects of Silymarin, published in 2017, researchers went so far as to say that silymarin promotes the inhibition of the inflammatory response generated during neurodegeneration.. Botanicals and their bioactive phytochemicals for women's health. The review went on to say that silymarin may be linked to lower rates of mortality in patients with cirrhosis and liver disease. If youre pregnant or breastfeeding, check with your doctor before using milk thistle. It is possibly effective in diabetes and indigestion (). Milk thistle is promoted as a dietary supplement for . 2014;2014:941085. doi:10.1155/2014/941085. In some studies, silibinin, an active component of milk thistle, has been shown to have estrogen-like effects. N-Acetylcysteine IBM Micromedex. "It helps to clear out the toxins and nourish the organ," says Justice. However, evidence suggests that milk thistle extracts might be useful in the treatment of mood disorders. This herb (also known as Silybum marianum) is native to the Mediterranean region. One important detoxifying ingredient is milk thistle. Brittany Lubeck, RD, is a nutrition writer and registered dietitian with a master's degree in clinical nutrition. World J Gastroenterol. Phytomedicine. If you are a Mayo Clinic patient, this could You may also consider consulting a practitioner who is trained in the use of herbal/health supplements. UltraThistle, the highest potency milk thistle formula, has been scientifically proven to be up to 10x more absorbable and up to 20x more effective than other standardized milk thistle formulas. Milk thistle may cause an allergic reaction in those with allergies to plants in the same family, like ragweed, chrysanthemum, marigold, and daisy. ; Extensively studied; effective in treatment of cirrhosis, hepatitis, chemical- or . Some, but not all, milk thistle supplements are vegan. Malaria. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Verywell Health's content is for informational and educational purposes only. Milk thistle is not recommended for children. 2018;8:65-74. doi:10.2147/PTT.S169333. . JIN_FK8R Please rate my stack I know I'm Fxxked up for now. Since milk thistle may lower blood sugar, people with diabetes should check with their doctor before taking the herb as it may make their blood sugar fall too low. Milk thistle may change the way your liver metabolizes certain drugs, like blood thinners, antibiotics, and anti-inflammatory medications. HHS Vulnerability Disclosure, Help The benefits of milk thistle remain unclear for this purpose and the limited research on milk thistle and breast milk has been done primarily in animals. Epub 2019 Nov 24. Is There a Reason Your Milk Thistle Isn't Working? Drug class: Herbal products. Neurological Disorders Milk thistle has long been used to alleviate the inflammation commonly associated with a host of neurological disorders such as dementia, Alzheimers, and Parkinsons Disease (8). All rights reserved. Available for Android and iOS devices. A double-blind controlled study. People with diabetes often have high cholesterol. Just amazing and timely information at your fingertips. While milk thistle is considered a noxious weed in various parts of the United States, it has little oral consumption value and is best absorbed in tablet or capsule supplement form, but can also be consumed as a tea or oral tincture. Its regularly used as a complementary therapy by people who have liver damage due to conditions like alcoholic liver disease, non-alcoholic fatty liver disease, hepatitis and even liver cancer (1, 5, 6). What Are the Risks of Taking Milk Thistle? Researchers believe that silymarin reduced the oxidative stress traditionally attributed with diabetes (7). The information and products shown on this website should not be interpreted as a substitute for physician evaluation or treatment. Brain Fog (anxiety, depression, ADHD), lots of medications. Occasionally, people report various digestive side effects. Join 45,000+ subscribers and receive the latest, useful and exclusive health and wellness articles, health tips, special offers and more - delivered direct to your inbox. Milk thistle has long been utilized as an anti-inflammatory agent offering numerous benefits to our liver, cholesterol, cardiovascular health, menopause symptom relief, and even gallbladder disorders. Studies have shown a decrease in blood sugar levels and an improvement in cholesterol in people with type 2 diabetes. However, the review's authors warned that the quality of the studies was poor and that more research is needed before milk thistle should be recommended for use. The benefits of milk thistle are believed to come from silymarin, an anti-inflammatory compound present throughout the entire plant, but highly concentrated in milk thistle seeds (4). Effects of Silybum marianum (L.) Gaertn. We know little about whether milk thistle is effective in people, as only a few well-designed clinical studies have been conducted. If you or anyone you know is living with obsessive compulsive disorder (OCD), proclaiming the symptoms of this mood disorder as debilitating is a vast understatement. J Diabetes Res. Uses of Lavender: Everything You Need to Know, 11 Popular Natural Remedies for the Common Cold, Natural Remedies for Alcohol Use Disorder, The therapeutic potential of milk thistle in diabetes, Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases, Silymarin as supportive treatment in liver diseases: a narrative review, Herbal product use by persons enrolled in the hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial, Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial, Effects of Silybum marianum (L.) Gaertn. Before Some animal studies have shown that milk thistle could be useful for reducing the side effects of cancer treatments (26, 27, 28). Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial. Other SSRIs on the market include Fluvoxamine (Luvox), Paroxatine (Paxil), and Sertraline (Zoloft) (3). Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Milk thistle benefits: Liver, skin, cholesterol, weight loss, and more Experts believe silymarin is the primary active ingredient of the herb. Beware that milk thistle can worsen depression, it doesn't act the same on everybody. More research is needed before a standard dosage of milk thistle can be recommended, so check with your healthcare provider. Milk thistle has been used as a traditional remedy for neurological conditions like Alzheimers and Parkinsons disease for over two thousand years (13). Research shows that the silymarin in milk thistle helps protect the liver from many industrial toxins, such as carbon tetrachloride. If we combine this information with your protected Cochrane Database Syst Rev. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). MeSH Milk thistle contains compounds that may support skin, liver, and bone health and enhance weight loss. It is possible to take too much, and liver toxicity has been observed in people with cancer taking silybin at very high doses (10 to 20 grams per day). Consult with your healthcare provider if you experience these and other side effects to find out the best way to proceed. One reported effect of milk thistle is that it can boost breast milk production in lactating mothers. other information we have about you. Thats an alarmingly high percentage, leaving roughly 1.1 million people of the 2.2 million OCD sufferers in the United States seeking alternative treatment options (2) and natural remedies. Thank you, {{form.email}}, for signing up. Some people have nausea, diarrhea, itching, and bloating. Milk thistle has been an important natural remedy for centuries of folk medicine practitioners. Milk Thistle Benefits - Verywell Health Milk Thistle. The study researchers hypothesize that milk thistle's antioxidant qualities make it a good candidate for treating conditions like cancer, hepatitis, NAFLD, diabetes, depression, and heart disease. Milk Thistle (Silybum marianum) for Anxiety? In clinical trials, milk thistle appears to be well tolerated in recommended doses. Milk thistlesupplementscontaining silymarin are commonly sold as teas or in capsule form, but are also available as tablets, soft gels, and liquid extracts. Accessed Oct. 30, 2020. People may also find it painful and worry about its effects on their appearance. Other drugs may interact with milk thistle, including prescription and over-the-counter medicines, vitamins, and herbal products. Suzanne Fisher, RD, founder of Fisher Nutrition Systems, has been a board-certified registered dietitian and licensed nutritionist for over 30 years. People who are allergic to artichokes, kiwi, ragweed, daisies, marigolds, and chrysanthemums are at higher risk. By lowering LDL "bad" cholesterol levels, milk thistle may lower the chance of developing heart disease. This article looks at the evidence to, Whats the life expectancy of someone with cirrhosis of the liver? We comply with the HONcode standard for trustworthy health information. Scan J Gastroenterol. Seeff, L.; Curto, T.; Szabo, G. et al. The nutritional content varies for each brand, so be sure to . Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination. Milk thistle can cause an allergic reaction, including a severe, potentially life-threatening allergic reaction (anaphylaxis). 2023 May;475(5):621-635. doi: 10.1007/s00424-023-02795-y. Also notable is the fact that, of the 40 subjects that completed this trial, none had any adverse events or side effects with milk thistle supplementation (7). https://www.wolterskluwercdi.com/facts-comparisons-online/. In fact, in studies where high doses were used for long periods, only about 1% of people experienced side effects (1).
How To Tell A Parent Their Child Is Failing,
List Of Current Social Movements 2022,
Articles M